Multi berry and Probiotics

 

This is the dietary supplement from Health OK, which is manufactured in South Korea. This one has 60 sachets, you can take 2 sachets in a day. This is good for 30 days. 

I bought it in Sn R and costs 899. It has the following flavors: Raspberry, Blueberry, Acai berry, Cranberry, and Aronia.  

I bought it because I researched that probiotics are good for your health especially of one has undergone a surgery. 

When Lilly and Stilwell first coined the term "probiotic," it meant "for life" in Greek. The phrase was coined as an alternative to the term "anti-biotic," which refers to a chemical made by one microorganism to destroy another. A collection of bacteria known as "probiotics" is added to meals to increase their nutritional value and maintain gut health.

Probiotics are recognized by the World Health Organization as the secondary immune system since they are effective at battling microbial illnesses and are affordable, safe, and harmless.

Probiotics' competitive interaction with pathogens that are present in the intestinal medium and that they inhibit is the basis for the notion of employing them to maintain health.

So is it effective?

I've been taking it for a week now and I have not experienced any differences in my overall health. I am stress-free, and I sometimes sleep late. I sometimes eat unhealthily but I seldom get sick.

I cannot tell if this product is effective. I bought this because I had surgery and has a surgical wound and I cannot tell if it helps in wound healing. 

References:

Ailioaie, L. M., & Litscher, G. (2021). Probiotics, photobiomodulation, and disease management: controversies and challenges. International Journal of Molecular Sciences, 22(9), 4942. https://doi.org/10.3390/ijms22094942

1. Milner, E., Stevens, B., An, M., Lam, V., Ainsworth, M., Dihle, P., ... & Segars, K. (2021). Utilizing Probiotics for the Prevention and Treatment of Gastrointestinal Diseases. Frontiers in Microbiology, 12, 689958. https://doi.org/10.3389/fmicb.2021.689958

2. Zhou, S., Chan, S. Y., Goh, B. C., Chan, E., Duan, W., Huang, M., & McLeod, H. L. (2005). Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs. Clinical Pharmacokinetics, 44(3), 279–304
3. Bermudez-Brito, M., Plaza-Díaz, J., Muñoz-Quezada, S., Gómez-Llorente, C., & Gil, A. (2012). Probiotic mechanisms of action. Annals of Nutrition and Metabolism, 61(2), 160–174. https://doi.org/10.1159/000342079
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What is the Eosinophilic Granulomatosis with Polyangiitis (EGPA) condition of Kris Aquino?

Kris Aquino has a rare auto-immune disease called Eosinophilic Granulomatosis with Polyangiitis (EGPA). Kris traveled to the United States in June. She stated in 2018 that she had been diagnosed with an autoimmune condition, and since then, she has been through different medical exams and therapies. 

What is this disease all about?

According to the website Allergology International,

https://www.jstage.jst.go.jp/article/allergolint/68/4/68_430/_article/-char/ja/

A rare form of anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis known as eosinophilic granulomatosis with polyangiitis (EGPA) (previously Churg-Strauss syndrome) is characterized by eosinophil-rich granulomatous inflammation and small to medium-size vessel vasculitis linked to bronchial asthma and eosinophilia. Research on EGPA has lagged behind other types of ANCA-associated vasculitis for a number of years due to its rarity and distinctive characteristics, such as eosinophilic inflammation.

Although EGPA patients often respond well to glucocorticoids, they frequently relapse. Currently, there isn't a proven treatment for EGPA, according to the results of numerous clinical trials. Mepolizumab was recently licensed for the treatment of EGPA after a randomized controlled trial demonstrated its therapeutic efficacy. Additionally, a number of fresh medications are being tested. Future research will be required to determine the best way to use these medications and to address unmet requirements, like relapse prevention.

Explain:

There is no proven treatment for EGPA, there is one licensed treatment Mepolizumab and it can be therapeutic after a controlled trial.  Steroids can be used but there is a relapse. 

The condition can harm key organs and can cause morbidity and mortality, This condition is bad for Kris, it can lead to mortality.

I hope Kris can survive her health problems. 

Let us pray for Kris recovery.

What is ANCA?

Antineutrophil cytoplasmic antibodies (ANCA) are antibodies that attack cytoplasmic components of neutrophils and monocytes (Lai, Leung, Rifkin and Lockwood, 1994). These antibodies are of major importance in detecting and classifying systemic vasculitides (Sinclair and Stevens, 2007),  like  eosinophilic granulomatosis with polyangiitis (eGPA, previously named Churg-Strauss Syndrome (CSS) (Sable-Fourtassou, Cohen, Mahr, Pagnoux, Mouthon, Jayne and French (2005). This is the condition of Kris Aquino. 

Different systemic forms of these vasculitides may harm key organs and cause significant morbidity and mortality as a result.

References: 

Lai, K. N., Leung, J. C., Rifkin, I., & Lockwood, C. M. (1994). Effect of anti-neutrophil cytoplasm autoantibodies on the intracellular calcium concentration of human neutrophils. Laboratory Investigation; a Journal of Technical Methods and Pathology, 70(2), 152-162.

Sinclair, D., & Stevens, J. M. (2007). Role of antineutrophil cytoplasmic antibodies and glomerular basement membrane antibodies in the diagnosis and monitoring of systemic vasculitides. Annals of clinical biochemistry, 44(5), 432-442.

Sablé-Fourtassou, R., Cohen, P., Mahr, A., Pagnoux, C., Mouthon, L., Jayne, D., ... & French Vasculitis Study Group*. (2005). Antineutrophil cytoplasmic antibodies and the Churg–Strauss syndrome. Annals of internal medicine, 143(9), 632-638.